Indian River Mosquito Control District is an independent special taxing district which was legislatively established in 1925 and provides mosquito control services in Indian River County. The District operates under Chapter 388, Florida Statutes and is recognized as a state-certified mosquito control program by the Florida Department of Agriculture and Consumer Services.

The District is organized according to the Council–Administrator form of government. As such, the Board of Commissioners (Board) sets policy, adopts legislation, and approves the budget. The Board appoints an administrator to conduct the day-to-day district business, to prepare the budget, to oversee department heads, and to recommend policy to the Board.

The District is governed by three commissioners, elected at large in the general election, by qualified electors residing in Indian River County.  Each member serves a four-year term, non-partisan office. Board officers are elected annually.